Gamma herpesvirus DNA and methods of use

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C424S229100, C530S350000

Reexamination Certificate

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06942863

ABSTRACT:
Isolated polynucleotides and polypeptides derived from the genome of swine gamma-herpesviruses are disclosed, including recombinant cells and vectors encoding such polypeptides and expressing such polynucleotides. Use of the novel polynucleotides as probes of the swine genome is also described. Assay methods employing antibodies against the isolated polypeptides are also disclosed.

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Simas, et al., “Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis,” Trends in Microbiology, vol. 6, No. 7, pp. 276-282 (Jul. 1998).
Bahr, et al., “Structural organization of a conserved gene cluster of Tupaia herpesvirus encoding the DNA polymerase, glycoprotein B, a probable processing and transport protein, and the major DNA binding protein,” Virus Research, pp. 123-136 (1999).
Ehlers, et al., “Detection of two novel porcine herpesviruses with high similarity to gammaherpesviruses,” Journal of General Virology, pp. 971-978 (1999).
Ulrich, et al., “Characterization of the DNA polymerase loci of the novel porcine lymphotropic herpesviruses 1 and 2 in domestic and feral pigs,” pp. 3199-3205 (1999).
Morozov, et al., “Detection of a Novel Strain of Porcine Circovirus in Pigs with Postweaning Multisystemic Wasting Syndrome,” vol. 36, No. 9, pp. 2535-2541 (Sep. 1998).

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