Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1995-07-17
1997-11-04
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424488, 424490, A61K 914
Patent
active
056837216
ABSTRACT:
Mecidinal specialty in galenic presentation and constituted in particular by a pastille, granule, pill, tablet or the like, adapted to be sucked by the user or with sublingual administration. At least one active product in microdispersed form within the substrate. Method of presenting a therapeutical composition for internal use, particularly for administration per os, in galenic presentation, and containing at least one active principle in solid form adsorbed on a substrate. The active product is distributed therein in the state of finely dispersed microparticles. The method is of the type comprising the phases of: dissolution of the starting active principle in an appropriate solvent; impregnation of the solution thus formed on a food support of appropriate structure pharmaceutically compatible with the active principle; and evaporation of the solvent from the solution adsorbed within the support, provoking reconstitution of the active principle by the formation of microcrystals adsorbed on the walls and within the substrate. The solvent is constituted by a binary system comprising a main solvent, of organic nature, and an adjuvant, of solid type at ambient temperature and soluble in the main solvent. The adjuvant in addition has lubricating properties.
REFERENCES:
patent: 4206209 (1980-06-01), Kracauer et al.
patent: 4985252 (1991-01-01), Jung et al.
patent: 5043167 (1991-08-01), Rotini et al.
patent: 5139774 (1992-08-01), Meinard et al.
patent: 5496565 (1996-03-01), Heinze et al.
Maury Marc
Perovitch Philippe
Benston, Jr. William E.
Page Thurman K.
LandOfFree
Galenic preparation of therapeutic composition comprising aspiri does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Galenic preparation of therapeutic composition comprising aspiri, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Galenic preparation of therapeutic composition comprising aspiri will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1831166