Galenic formulations with programmed release containing naproxen

Details Galenic formulations with programmed release containing naproxen Galenic formulations with programmed release containing naproxen

1989-04-12

1989-12-19

Dixon, Jr., William R.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424470, 424472, A61K 924

Patent

active

048881783

ABSTRACT:
A galenic formulations are disclosed with programmed release, to be administered orally containing as the active ingredient a compound having antiphlogistic, analgesic and antipyretic activity like, for instance, an arylacetic or an arylpropionic acid, and pharmaceutically acceptable salts thereof. In these new formulations, a portion of the active ingredient is released in a short time, so that the drug can quickly develop its therapeutic action and reach the necessary hematic levels, while the remaining portion of the active constituent is released in a longer interval of time so as to allow therapeutic coverage until subsequent administration. The therapeutic coverage can even last twenty-four hours. Thus, the new galenic formulations object of the present invention are suitable for administration one a day.

REFERENCES:
patent: 2793979 (1957-05-01), Svedres
patent: 3044938 (1962-07-01), Halley
patent: 4012498 (1977-03-01), Kornblum et al.
patent: 4167588 (1979-09-01), Sheth et al.
patent: 4572833 (1986-02-01), Pedersen et al.
patent: 4720387 (1988-01-01), Sakamoto et al.

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