Galenic formulations for oral use of rhein derivatives with dela

Details Galenic formulations for oral use of rhein derivatives with dela Galenic formulations for oral use of rhein derivatives with dela

1987-09-30

1989-08-29

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424489, 424490, 424493, 424495, 424497, 424456, A61K 916

Patent

active

048615994

ABSTRACT:
Several methods are disclosed for the preparation of oral pharmaceutical forms with delayed release of rhein and its derivatives. The pharmaceutically active ingredient is provided in the form of granules, coated with at least one of polyvinylpyrrolidone, shellac and hydroxypropylmethyl cellulose. The desired effect of the coating is to slow release of the pharmaceutically active ingredient by resisting gastric juices in the stomach, but gradually dissolving in the intestines.

REFERENCES:
patent: 4666703 (1987-05-01), Kopf

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