Galenic forms of prolonged release verapamil and medicaments con

Details Galenic forms of prolonged release verapamil and medicaments con Galenic forms of prolonged release verapamil and medicaments con

1986-09-30

1989-05-23

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

A61K 922, A61K 932, A61K 944

Patent

active

048329584

ABSTRACT:
The new galenic forms of prolonged release verapamil consist of microgranules containing a pharmacologically acceptable acid-addition salt or verapamil as active substance combined with at least one wetting agent, said microgranules being coated with a microporous membrane consisting of at least one pharmacologically acceptable adjuvant (such as plasticizer, filler, lubricant, etc) and of at least one film forming mixture composed of (1) at least one insoluble acrylic or methacrylic polymer and (2) a substance which is insoluble in the acid gastric medium, but soluble in the intestine.

REFERENCES:
Einig CA. 98: 59901w (1983) of Ger. Off. DE 3113901, Oct. 28, 1982.

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