Galactose derivative, drug carrier and medicinal composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S023000, C514S053000, C514S054000, C514S061000

Reexamination Certificate

active

07820629

ABSTRACT:
The object of the present invention is to provide a novel and useful galactose derivative, which is a component of a drug carrier by which a medicine can be efficiently transferred into the liver, a drug carrier comprising the derivative, and a pharmaceutical composition comprising the drug carrier and a medicine.The present invention relates to a galactose derivative represented by the following general formula (I) a drug carrier comprising the derivative and a cationic lipid, and a pharmaceutical composition comprising the carrier and a medicine (preferably a double-stranded RNA, a double-stranded DNA, an oligo nucleic acid).wherein, R1represents hydrogen, an alkyl having 1 to 10 carbons which may be substituted or 1-(D)-deoxylactito-1-yl; R2represents a saturated or unsaturated fatty acid residue having 10 to 30 carbon atoms.

REFERENCES:
patent: 5705188 (1998-01-01), Junichi et al.
patent: 685457 (1995-12-01), None
patent: 723972 (1996-07-01), None
patent: 1637144 (2006-03-01), None
patent: 7-188274 (1995-07-01), None
patent: 9-235292 (1997-09-01), None
patent: WO-9419314 (1994-09-01), None
patent: WO-2004105774 (2004-12-01), None
Kitamoto et al. J. Bioscience and Bioengineering (2002), vol. 94, pp. 187-201.
Rico-Lattes et al. Colloids and Surfaces A: Physicochemical and Engineering Aspects 123-124 (1997) 37-48.
Rico-Lattes, Isabelle et al. Synthesis of New Sugar-Based Surfactants Having Biological Applications: Key Role of Their Self-Association, Colloids and Surfaces, A: Physicochemical and Engineering Aspects, 1997, vol. 123-124, pp. 37-48.
Andre-Barrnes, Christiane et al. New Double-Chain Surfactants Derived From Glucose and a Lactose—An Alternative to AOT, New Journal of Chemistry, 1995, vol. 19, No. 4, pp. 345-347.
Wilk, Kazimiera A. et al., Preparation and Properties of New Lactose-Based Surfactants, Journal of Surfactants and Detergents, 2001, vol. 4, No. 2, pp. 155-161.
Ricoul, Florence et al., Phase Equilibria and Equation of State of a Mixed Cationic Surfactant-Glycolipid Lamellar System, Langmuir, 1998, vol. 14, No. 10, pp. 2645-2655.
Garrigues, Jean-Christophe et al., Comparative Study for the Incorporation of a New Antifungal Family of Neoglycolipids and Amphotericin B in Monolayers Containing Phospholipids and Cholesterol or Ergosterol, Langmuir, 1998, vol. 14, No. 20, pp. 5968-5971.
Ricoul, Florence et al., An Efficient Method to Determine Isothermal Ternary Phase Diagrams Using Small-Angle X-Ray Scattering, Journal of Physical Chemistry B, 1998, vol. 102, No. 15, pp. 2769-2277.
Rico-Lattes, Isabelle et al., A Short Route to Analogs of Galactosphingolipids Possessing Anti-HIV and Anti-Aspergillus Activity, New Journal of Chemistry, 1995, vol. 19, No. 4, pp. 341-344.

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