Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2007-02-28
2010-10-26
Lewis, Patrick T (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S023000, C514S053000, C514S054000, C514S061000
Reexamination Certificate
active
07820629
ABSTRACT:
The object of the present invention is to provide a novel and useful galactose derivative, which is a component of a drug carrier by which a medicine can be efficiently transferred into the liver, a drug carrier comprising the derivative, and a pharmaceutical composition comprising the drug carrier and a medicine.The present invention relates to a galactose derivative represented by the following general formula (I) a drug carrier comprising the derivative and a cationic lipid, and a pharmaceutical composition comprising the carrier and a medicine (preferably a double-stranded RNA, a double-stranded DNA, an oligo nucleic acid).wherein, R1represents hydrogen, an alkyl having 1 to 10 carbons which may be substituted or 1-(D)-deoxylactito-1-yl; R2represents a saturated or unsaturated fatty acid residue having 10 to 30 carbon atoms.
REFERENCES:
patent: 5705188 (1998-01-01), Junichi et al.
patent: 685457 (1995-12-01), None
patent: 723972 (1996-07-01), None
patent: 1637144 (2006-03-01), None
patent: 7-188274 (1995-07-01), None
patent: 9-235292 (1997-09-01), None
patent: WO-9419314 (1994-09-01), None
patent: WO-2004105774 (2004-12-01), None
Kitamoto et al. J. Bioscience and Bioengineering (2002), vol. 94, pp. 187-201.
Rico-Lattes et al. Colloids and Surfaces A: Physicochemical and Engineering Aspects 123-124 (1997) 37-48.
Rico-Lattes, Isabelle et al. Synthesis of New Sugar-Based Surfactants Having Biological Applications: Key Role of Their Self-Association, Colloids and Surfaces, A: Physicochemical and Engineering Aspects, 1997, vol. 123-124, pp. 37-48.
Andre-Barrnes, Christiane et al. New Double-Chain Surfactants Derived From Glucose and a Lactose—An Alternative to AOT, New Journal of Chemistry, 1995, vol. 19, No. 4, pp. 345-347.
Wilk, Kazimiera A. et al., Preparation and Properties of New Lactose-Based Surfactants, Journal of Surfactants and Detergents, 2001, vol. 4, No. 2, pp. 155-161.
Ricoul, Florence et al., Phase Equilibria and Equation of State of a Mixed Cationic Surfactant-Glycolipid Lamellar System, Langmuir, 1998, vol. 14, No. 10, pp. 2645-2655.
Garrigues, Jean-Christophe et al., Comparative Study for the Incorporation of a New Antifungal Family of Neoglycolipids and Amphotericin B in Monolayers Containing Phospholipids and Cholesterol or Ergosterol, Langmuir, 1998, vol. 14, No. 20, pp. 5968-5971.
Ricoul, Florence et al., An Efficient Method to Determine Isothermal Ternary Phase Diagrams Using Small-Angle X-Ray Scattering, Journal of Physical Chemistry B, 1998, vol. 102, No. 15, pp. 2769-2277.
Rico-Lattes, Isabelle et al., A Short Route to Analogs of Galactosphingolipids Possessing Anti-HIV and Anti-Aspergillus Activity, New Journal of Chemistry, 1995, vol. 19, No. 4, pp. 341-344.
Ohgi Tadaaki
Sonoke Satoru
Ueda Toshihiro
Lewis Patrick T
McDermott Will & Emery LLP
Nippon Shinyaku Co. Ltd.
LandOfFree
Galactose derivative, drug carrier and medicinal composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Galactose derivative, drug carrier and medicinal composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Galactose derivative, drug carrier and medicinal composition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4163142