Galactosamine substitute of poly-.omega.-substituted-L-glutamic

Details Galactosamine substitute of poly-.omega.-substituted-L-glutamic Galactosamine substitute of poly-.omega.-substituted-L-glutamic

1991-04-23

1992-06-23

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Peptides containing saccharide radicals, e.g., bleomycins, etc.

530345, 530395, 530402, C07K 900, C07K 100, C07K 300, C07K 1300

Patent

active

051244373

ABSTRACT:
A galactosamine substituted poly-.omega.-alkyl (or benzyl)-L-glutamic acid (or aspartic acid) is provided and comprises a polypeptide having the recurring unit represented by the formula: ##STR1## wherein X has a value of 60 to 250; n is 1 or 2; and R represents a lower alkyl group or benzyl group, in which a part or all of the peptide in said polypeptide is substituted by an .omega.-galactosamyl-L-glutamic acid (or aspartic acid) residue represented by the general formula: ##STR2## wherein n is as indicated.

REFERENCES:
R. Guenin et al., Immunobiology (Stuttgart) 170:412-18, 1985, abstracted at Chemical Abstracts 105:583, #40956j, 1986.
C. J. Steer et al., Journal of Biological Chemistry 254:4457-4461, 10 Jun. 1979.

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