Gag gene primers for the detection of HIV-1

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 6, 435 912, 435810, 536 2432, 536 2433, C12Q 168, C07H 2104, C12P 1934

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active

059087439

ABSTRACT:
The present invention provides improved primers for the polymerase chain reaction (PCR) amplification of a nucleic acid sequence from the gag gene of the human immunodeficiency virus type 1 (HIV-1). The primers and amplification methods of the invention enable the detection of all HIV-1 group M isolates with nearly uniform efficiency.

REFERENCES:
patent: 5386022 (1995-01-01), Sninsky et al.
patent: 5389512 (1995-02-01), Sninsky et al.
patent: 5599662 (1997-02-01), Respess
patent: 5695926 (1997-12-01), Cros et al.
patent: 5702926 (1997-12-01), Cummins et al.
Kwok et al., 1990, "Effects of Primer--Template Mismatches on the Polymerase Chain Reaction: Human Immunodeficiency Virus Type 1 Model Studies," Nucleic Acids Research, 18 (4): 999-1005.
Kellogg et al., 1990, "Detection of Human Immunodeficiency Virus," PCR Protocols: A Guide to Methods and Applications: 337-347.
Jackson et al., 1991, "Non-isotopic Polymerase Chain Reaction Methods for the Detection of HIV-1 in Ugandan Mothers and Infants," AIDS 5 1463-1467.
Coutlee et al., 1991, "The Polymerase Chain Reaction: A New Tool for the Understanding and Diagnosis of HIV-1 Infection at the Molecular Level," Molecular and Cellular Probes 5:241-259.
1993 Product Insert for Amplicor.TM. HIV-1 Test, pp. 1-11.
Kwok et al., 1994, "A Guide to the Design and Used of Mismatched and Degenerate Primers," PCR Methods & Applications 3:S39-S47.
Fransen et al., 1994, "Design and Evaluation of New, Highly Sensitive and Specific Primers for Polymerase Chain Reaction Detection of HIV-1 Infected Primary Lymphocytes," Molecular and Cellular Probes 8: 317-322.
Meyers et al., 1994 Human Retroviruses and AIDS, Los Alamos National Laboratory, Los Alamos New Mexico: pp. I1-IA49.
Arnold et al., Nov. 1995, "HIV Type 1 Sequence Subtype G Transmission From Mother to Infant: Failure of Variant Sequence Species to Amplify in the Roche Amplicor Test," AIDS Research and Human Retroviruses 11(8): 999-1001.
Meyers et al., 1996 Human Retroviruses and AIDS, Los Alamos National Laboratory, Los Alamos New Mexico: pp. I1-I19 and I93-I128.
1996 Product Insert for Amplicor HIV-1 Monitor.TM. Test, pp. 1-30.
Lyamuya et al., Jan. 1997, "Comparison of In-House and Commercial Sample Preparation and PCR Amplification Systems for Detection of Human Immunodeficiency Virus type 1 DNA in Blood Samples from Tanzanian Adults," Journal of Clinical Microbiology 35 (1): 278-280.

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