GABA and L-glutamic acid analogs for antiseizure treatment

Details GABA and L-glutamic acid analogs for antiseizure treatment GABA and L-glutamic acid analogs for antiseizure treatment

1999-02-04

2000-10-31

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 31195

Patent

active

061403660

ABSTRACT:
A compound of the formula ##STR1## wherein R.sub.1 is a straight branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

REFERENCES:
patent: 4372974 (1983-02-01), Fish

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