GABA and L-glutamic acid analogs for antiseizure treatment

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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A61K 31195

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active

06117906&

ABSTRACT:
A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

REFERENCES:
patent: 3624102 (1971-11-01), Brown
patent: 3627889 (1971-12-01), Mendham
patent: 3676447 (1972-07-01), Skinner
patent: 3947492 (1976-03-01), Perekalin
patent: 4322440 (1982-03-01), Fish

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