Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1998-08-21
2000-10-17
Saunders, David
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303892, 530864, C07K 1618
Patent
active
061334286
ABSTRACT:
A substantially pure protein, Gab1, that binds to Grb2 is disclosed. Isolated nucleic acid molecules that encode Gab1 is disclosed. Pharmaceutical compositions comprising a pharmaceutically acceptable carrier in combination with nucleic acid molecules are disclosed. Fragments of nucleic acid molecules that encode Gab1 having at least 10 nucleotides and oligonucleotide molecule comprising a nucleotide sequence complimentary to a nucleotide sequence of at least 10 nucleotides are disclosed. Recombinant expression vectors that comprise the nucleic acid molecule that encode Gab1, and host cells that comprise such recombinant vectors are disclosed. Antibodies that bind to an epitope on Gab1 are disclosed. Methods of identifying inhibitors, activators and substrates of Gab1 are disclosed. Antisense compounds and methods of using the same are disclosed.
Holgado-Madruga Marina
Wong Albert J.
DeCloux Amy
Saunders David
Thomas Jefferson University
LandOfFree
Gab1, a Grb2 binding protein, and compositions for making and me does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Gab1, a Grb2 binding protein, and compositions for making and me, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gab1, a Grb2 binding protein, and compositions for making and me will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-470391