G protein-coupled receptor protein and DNA thereof

Details G protein-coupled receptor protein and DNA thereof G protein-coupled receptor protein and DNA thereof

2007-07-31

2007-07-31

Ulm, John (Department: 1649)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S007210, C435S252300, C435S320100, C530S350000, C536S023500

Reexamination Certificate

active

10398870

ABSTRACT:
The present invention aims at providing a useful and novel G protein-coupled receptor protein and DNA thereof.The G protein-coupled receptor protein of the present invention and the like, and the polynucleotides encoding the receptor protein and the like, are useful for; 1) determination of ligands (agonists); 2) preparation of antibodies and antisera; 3) construction of recombinant receptor protein expression systems; 4) development of the receptor binding assay systems using the expression systems and screening of pharmaceutical candidate compounds; 5) effecting drug design based on comparison with structurally similar ligand receptors; 6) reagents for preparation of probes and PCR primers for gene diagnosis; 7) production of transgenic animals; and 8) pharmaceutical drugs for the gene prophylaxis and gene therapy.

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