G-protein coupled receptor ligands and methods

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007200, C436S501000

Reexamination Certificate

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10411545

ABSTRACT:
The present invention relates to RF-amide peptides and their use for treating, preventing and curing neurological and metabolic medical disorders. The invention also relates to methods for modulating a G-protein coupled receptor and for identifying substances which modulate the receptor.

REFERENCES:
patent: 6927041 (2005-08-01), Zhelnin et al.
patent: 2003/0223992 (2003-12-01), Jiang et al.
patent: 2004/0248790 (2004-12-01), Hinuma et al.
patent: 1 207 201 (2002-05-01), None
patent: WO97/37967 (1997-10-01), None
patent: WO99/32519 (1999-07-01), None
patent: WO 00/11015 (2000-03-01), None
patent: WO 00/22131 (2000-04-01), None
patent: WO 00/31258 (2000-06-01), None
patent: WO00/66151 (2000-11-01), None
patent: WO 00/78809 (2000-12-01), None
patent: WO 01/16316 (2001-03-01), None
patent: WO 01/16316 (2001-03-01), None
patent: WO 01/48189 (2001-07-01), None
Jiang-Y et al. J. Biol. Chem. 278(30)27652-27657)2003.
Nagai-G et al., Biochem. Biophys. Res. Com. 248(733-737)1998.
Fukusumi-S. et al., J. Biol. Chem. 278(46387-46395)2003.
Bowie et al., 1990, Science 247:1306-1310.
Guo-HH et al. PNAS 101(25)9205-9210, 2004.
PCT/US03/11159 Patent Corporation Treaty International Search Report (5 pgs.).
Ensembl genome database entry, SP9155, 2006.
Takayasu et al., A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice. Proc Natl Acad Sci U S A. May 9, 2006;103(19):7438-43.
Chartrel et al., Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc. Natl. Acad. Sci. U S A. Dec. 9, 2003;100(25):15247-52.
Chartrel et al., Identification of 26RFa from frog brain: a novel hypothalamic neuropeptide with orexigenic activity in mammals. Ann. N.Y. Acad Sci. Apr. 2005;1040:80-3.
Do Rego et al., Behavioral effects of 26RFamide and related peptides. Peptides (2006) in press.
Moriya et al., RFamide peptide QRFP43 causes obesity with hyperphagia and reduced thermogenesis in mice. Endocrinology. Jun. 2006;147(6):2916-22.
Lee et al., Discovery and mapping of ten novel G protein-coupled receptor genes. Gene (2001) 275: 83-91.
Sequence Disclosure-Genbank Accession No. BB200502, Jun. 30, 2000.
Sequence Disclosure-Genbank Accession No. BB634210, Aug. 31, 2001.
Sequence Disclosure-Genbank Accession No. BB613620, Aug. 31, 2001.
Sequence Disclosure-Genbank Accession No. XM—071001, Aug. 1, 2002.
Sequence Disclosure-Genbank Accession No. AL161733, Dec. 3, 2001.
Sequence Disclosure-Genbank Accession No. BF167714, Oct. 27, 2000.
Liu et al., J. Biol. Chem. (2001) 276(40):36961-36969.
Li et al., Brain Research (1999) 848:26-34.
Ying Jiang et al, Identification and Characterization of a Novel RF-amide Peptide for Orphan G-Protein-Coupled Receptor SP9155, Journal of Bio Chem, vol. 278, No. 30, pp. 27652-27657, 2003.
Ying Jiang et al, Identification and Characterization of a Novel Peptide for Orphan G-Protein Coupled Receptor SP9155, Biopolymers, vol. 71, No. 3, pp. 296, 2003.
Lee, Dennis K., et al., Discovery and mapping of ten novel G protein-coupled receptor genes. Gene (2001) 275:83-91.
Jiang, Ying, et al., PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide Mammalian Genome (2003) 14:341-349.
Klein, Robert F., et al., Confirmation and Fine Mapping of Chromosomal Regions Influencing Peak Bone Mass in Mice. J. Bone Min. Res. (2001) 16(11):1953-1961.
Benes, Helen et al., Chromosomal Mapping of Osteopenia-Associated Quantitative Trait Loci Using Closely Related Mouse Strains. J. Bone Min. Res (2000) 15(4):626-633
Joost, Patrick, et al., Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biology 2002, 3(11):research0063.1-0063.16.

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