G-coupled receptor showing selective affinity for ATP

Details G-coupled receptor showing selective affinity for ATP G-coupled receptor showing selective affinity for ATP

2007-10-30

2007-10-30

Ulm, John D. (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100

Reexamination Certificate

active

10977395

ABSTRACT:
The present invention relates to an isolated G-protein coupled receptor, nucleic acid sequence encoding the receptor, and host cells capable of expressing the receptor. The invention further comprises methods for detecting the expression of a G-protein coupled receptor, and methods for identifying agonists or antagonists of the receptor. The invention still further encompasses methods for preparing an isolated G-protein coupled receptor.

REFERENCES:
patent: 5981223 (1999-11-01), Sathe et al.
patent: 6114127 (2000-09-01), Bergsma et al.
Chaplinski et al., Study of Differentiation of Fresh Myeloid Leukemic Cells by Physiologic Agents That Induce a Humen Promyelocytic Leukemic Line (HL-60) to Differentiate. 1896, Leukemia Research 10(6):611-617, Abstract Only.
Jiang et al., Extracellular ATP Triggers Cyclic AMP-Dependent Differentation of HL-60 Cells, 1997, Biochem. and Biophys. Res. Comm. 232:626-630.
Communi D. & Boeynaems J.M., Receptors responsive to extracellular pyrimidine nucleotides, Mar. 1997, TIPS, vol. 18, pp. 83-86.
Communi D. et al, Cloning of a Human Purinergic P2Y Receptor Coupled to Phospholipase C and Adenyl Cyclase, Dec. 1997, The Journal of Biological Chemistry, vol. 272 No. 51, pp. 31969-31973.
J.A. Parsons, M.A., B.M., B.Ch., Peptide Hormones, University Park Press, Jun. 1976.
Genbank Accession No. AA321112 entered Apr. 19, 1997.
Genbank Accession No. N34073 entered Jan. 11, 1996.
Hammer, et al., 1990, Spontaneous Inflammatory Disease in Transgenic Rats Expressing HLA-B27 and Human B2m: An Animal Model of HLA-B27-Associated Human Disorders, Nov. 30, 1990, Cell Press, vol. 63, 1099-1112.
John J. Mullins, Linda, J. Mullins, Transgenesis in Nonmurine Species, Oct. 1993, Hypertension, vol. 22, No. 4.

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