G+C-rich binding protein

Details G+C-rich binding protein G+C-rich binding protein

2008-05-06

2008-05-06

Chernyshev, Olga N. (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100

Reexamination Certificate

active

07368538

ABSTRACT:
A novel transcription regulator of G+C-rich promoters, the murine G+C-rich Promoter Binding Protein (mGPBP), and its interaction pattern with other transcription factors are disclosed. A human homologue of mGPBP, hGPBP, is described as well.

REFERENCES:
patent: 5580703 (1996-12-01), Kotin et al.
patent: WO 00/58473 (2000-05-01), None
International Search Report from PCT/US03/07870 dated Jan. 6, 2005.
Kudo, S., “Methyl-CpG-Binding Protein MeCP2 Represses Sp1-Activated Transcription of the Human Leukosialin Gene When the Promoter is Methylated,” Molecular and Cellular Biology, vol. 18, No. 9, pp. 5492-5499 (Sep. 1998).

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