Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-11-21
2006-11-21
Housel, James (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S004000, C435S007920
Reexamination Certificate
active
07138245
ABSTRACT:
Analyses of serum samples for the presence and amount of either of the two subunits of human Factor XIII protein are used as a means of eliminating a significant source of error that arises in the testing of serum and plasma. For serum samples, a negative result of an analysis for the presence of subunit a is a means of verifying that a sample is indeed serum, while a negative or positive result for subunit a serves to distinguish serum (negative) from plasma (positive). A positive result for the presence of subunit b is a means of verifying that the sample is either serum or plasma and not any other biological fluid. A quantitative analysis of subunit b is a means of verifying that the sample is of the intended volume rather than having been reduced in volume due to improper sampling. A quantitative analysis of subunit b is also a means of verifying the dilution of a sample of either serum or plasma.
REFERENCES:
patent: 4325867 (1982-04-01), Eberle et al.
patent: 4601977 (1986-07-01), Ogawa et al.
patent: 4624927 (1986-11-01), Fukushima et al.
patent: 5015588 (1991-05-01), Lee et al.
patent: 5401638 (1995-03-01), Carney et al.
patent: 5688919 (1997-11-01), Hock
patent: 5981180 (1999-11-01), Chandler
patent: 6660486 (2003-12-01), Binder et al.
Katona et al., “Enzyme-linked immunosorbent assay for the determination of blood coagulation factor XIII A-subunit in plasma and in cells lysates”, Journal of Immunological Methods 258 (2001), 127-135.
. Murdock et al., “Development and Evaluation of ELISAS for Factor XIIIA and XIIIB Subunits in Plasma”, Thrombosis Research, 67; 73-79, 1992.
Ariens, et al., “Subunit Antigen and Activity Levels of Blood Coagulation Factor XIII in Healthy Individuals”, Arterioscler. Thromb. Vasc. Biol., Aug. 1999, pp. 2012-2016.
Katona et al., “Simple, Quick One-step ELISA Assay for the Determination of Complex Plasma Factor XIII (A2B2)”, Thromb. Haemost. 2000, 83: 268-73.
Kroll, The subunit composition of factor XIII proteins in normal and factor XIII deficient plasma and serum analysed by line immunmoelectrophoresis:Clinica Chemical Acta (1989); vol. 179 pp. 279-284.
Yorifuji et al., B Protein of factor XIII: differentiation between free B and complexed B; Blood (1998); vol. 72 pp. 1645-1650.
Achyuthan, K.E. et al. “A microtiter plate assay for factor XIII A-chain-fibrin interactions,”Anal. Biochem. 1994, pp. 43-48, vol. 219.
Ariens et al.; “Subunit antigen and activity levels of blood coagulation factor XIII in healthy individuals: Relation to sex, age, smoking, and hypertension”; 1999,Arteriosclerosis Thromobosis and Vascular Biology, vol. 19, pp. 2012-2016.
Jenny and Jackson-Tarentino, “Causes of unsatisfactory performance in proficiency testing,”Clinical Chemistry(2000) 46(1):89-99.
Gniewek et al., Monoclonal Antibodies specific for Human Plasma Factor XIII B-subunit and their use in Purification of Human Plasma Factor-XIII by Immunoaffinity Chromatography,Federation Proceedings(1985) 44 (4): 1070.
Katona et al.; “A simple quick one step ELISAS for Factor XIIIA and XIIIB subunits in plasma”; 1992,Thrombosis Research, vol. 67, pp. 268-273.
Kasahara, K. et al., ““A” subunit of factor XIII present on bovine platelet membrane and mediates collagen-induced platelet activation,”Thrombosis Res. 1988, pp. 253-263, vol. 50.
Mitkevich, O.V. et al., “Coagulation factor XIIIa undergoes a conformational change evoked by glutamine substrate,”J. Biol. Chem. Jun. 5, 1998, pp. 14387-14391, vol. 273, No. 23.
Murdock et al., “Development and evaluation of elisas for factor XIIIA and XIIIB subunits in plasma,”Thrombosis Research(1992) 67:73-79.
Musbek et al.; “Novel aspects of blood coagulation factor XIII. I. Structure, distribution, activation, and function”; 1996,Critical Reviews in Clinical Laboratory Sciences, vol. 33, pp. 357-421.
Nagy et al.; “Biosynthesis of factor XIII B subunit”; 1986,Blood, vol. 68, pp. 1272-1279.
Nonaka et al.; “Molecular cloning of the b subunit of mouse coagulation factor XIII and assignment of the gene to chromosome 1: Close evolutionary relationship to complement factor H”; 1993,Genomics, vol. 15, pp. 535-542.
Schweinie, J.E. et al.; Monoclonal Antibodies Specific for Human Plasma Factor XIII B Subunit and Their Use in the Purification of Human Plasma Factor XIII by Immunoaffinity Chromatography;Blood Coagulation, abstract No. 3857.
Takagi, J. et al. “Subunit B of factor XIII is present in bovine platelets,”Thrombosis Res. 1988, pp. 767-774, vol. 50.
Binder Steven R.
Goodrich Jodi L.
Safarian Zara
Bio-Rad Laboratories, Inc.
Heines M. Henry
Housel James
Lam Amy
Townsend and Townsend / and Crew LLP
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