Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1996-07-30
1999-08-31
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
4241341, 4241921, 435 697, 435471, 530350, C07K 1900
Patent
active
059455136
ABSTRACT:
The present invention relates to fusion proteins having gp39 protein sequences, which fusion proteins bind to the B cell antigen, CD40. More specifically, the invention relates to fusion proteins having gp39 protein sequences attached to a polypeptide having an amino terminal secretory signal sequence to allow export of the fusion protein out of the recombinant host cell in which it is produced. The fusion proteins of this invention may be useful for promoting B cell proliferation.
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Aruffo Alejandro
Hollenbaugh Diane
Ledbetter Jeffrey A.
Bristol-Myers Squibb
Chan Christina Y.
Gambel Phillip
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