Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1987-10-26
1991-04-16
Schwartz, Richard A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
435 697, 435 91, 435170, 435171, 4351723, 4352402, 4352523, 435254, 435257, 435235, 435258, 4353201, 536 27, 530351, 530412, 935 10, 935 12, 935 22, 935 59, 935 66, C07K 300, C02K 1300, C02K 1500, C12N 1511
Patent
active
050083732
ABSTRACT:
Fusion proteins comprise a first amino acid sequence and a second amino acid sequence. The first amino acid sequence is derived from a retrotransposon or an RNA retrovirus and confers on the fusion protein the ability of assemble into particles; an example is the product of the TYA gene of the yeast retrotransposon Ty. The second amino acid sequence is biologically active; for example, it may be antigenic. So particles formed of the fusion proteins may be useful in vaccines or in diagnostic or purification applications
REFERENCES:
patent: 4722840 (1988-02-01), Valenzuela et al.
patent: 4925784 (1990-12-01), Crowl et al.
Haynes et al., 1986, Bio/Technology, 4:637.
Mellor et al., 1985, Nature, 317:243.
Adams Sally E.
Kingsman Alan J.
Kingsman Susan M.
Malim Michael H.
Mellor Elizabeth J. C.
Oxford Gene Systems Limited
Peet Richard C.
Schwartz Richard A.
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