Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2003-08-11
2009-12-29
O'Hara, Eileen B (Department: 1644)
Chemistry: molecular biology and microbiology
Vector, per se
C435S069700, C435S070100, C435S071100, C435S071200, C435S328000, C435S329000, C435S358000, C435S365000
Reexamination Certificate
active
07638323
ABSTRACT:
The present invention provides compositions and methods for treating or preventing hyperacute rejection.
REFERENCES:
patent: 5225538 (1993-07-01), Capon et al.
patent: 5428130 (1995-06-01), Capon et al.
patent: 5455165 (1995-10-01), Capon et al.
patent: 5514582 (1996-05-01), Capon et al.
patent: 5516964 (1996-05-01), Umansky et al.
patent: 5714147 (1998-02-01), Capon et al.
patent: 6136310 (2000-10-01), Hanna et al.
GenBank Accession No. NP—033177 (Jul. 2008).
GenBank Accession No. AJ417818 (Jun. 2002).
GenBank Accession No. XM—140694 (Oct. 2002).
GenBank Accession No. XP—140694 (Oct. 2002).
GenBank Accession No. XM—006867 (Aug. 2002).
GenBank Accession No. XP—006867 (Aug. 2002).
GenBank Accession No. NP—663625 (Mar. 2008).
GenBank Accession No. NM—145650 (Mar. 2008).
GenBank Accession No. CAD10625 (Apr. 2005).
GenBank Accession No. BAB66024 (May 2007).
GenBank Accession No. CAA79610 (Nov. 1995).
GenBank Accession No. AAA73558 (Jul. 1995).
GenBank Accession No. BAB30163 (Oct. 2006).
GenBank Accession No. P50127 (Jun. 2008).
GenBank Accession No. NM—009151 (Jul. 2008).
GenBank Accession No. Z19550 (Nov. 1995).
GenBank Accession No. AK016248 (Oct. 2006).
GenBank Accession No. L36152 (Jul. 1995).
Dorling et al., “Prospects for xenografting”,Curr. Opin. Immunol., 6(5):765-769 (1994).
Ye et al., “The pig as a potential organ donor for man. A study of potentially transferable disease from donor pig to recipient man.”,Transplantation, 57(5):694-703 (1994).
Michaels et al., “Xenotransplant-associated zoonoses. Strategies for prevention”,Transplantation, 57(1):1-7 (1994).
Calne, R.Y., “Organ transplantation between widely disparate species.”,Transplant. Proc., 2(4):550-556 (1970).
Bach et al., “Endothelial cell activation and thromboregulation during xenogrdt rejection”,Immunol. Rev., 141:5-30 (1994).
Magee, et al., “Xenograft rejection - molecular mechanisms and therapeutic implications”,Therap. Immunol., 1(1):45-58 (1994).
Platt et al., “Endothelial cell antigens recognized by xenoreactive human natural antibodies”,Transplantation, 50(5):817-822 (1990).
Good et al., “Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans”,Transplant. Proc., 24(2):559-562 (1992).
Holgersson et al., “Carbohydrate specificity of human immunoglobulinM antibodies with pig lymphocytotoxic activity”,Transplant. Proc., 24(2):605-608 (1992).
Oriol et al., “Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation”,Transplantation, 56(6):1433-1442 (1993).
Galili, U., “Interaction of the natural anti-Gal antibody with alpha-galactosyl epitopes: a major obstacle for xenotransplantation in humans”,Immunol. Today, 14 (10):480-482 (1993).
Sandrin et al., “Anti-pig IgM antibodies in human serum react predominantly with Gal(α1-3)Gal epitopes”,Proc. Natl. Acad Sci. USA, 90(23):11391-11395 (1993).
Cairns et al., “Xenografts - future prospects for clinical transplantation”,Immunol. Lett., 29(1-2):167-170 (1991).
Rydberg et al., “Studies on the removal of anti-pig xenoantibodies in the human by plasmapheresis/immunoadsorption”,Xenotransp/antation, 2:253-263 (1995).
Soares et al., “In vivo depletion of xenoreactive natural antibodies with an anti-μ monoclonal antibody”,Transplantation, 56(6):1427-1433 (1993).
Soares et al., “In vivo IgM depletion by anti-μ monoclonal antibody therapy. The role of IgM in hyperacute vascular rejection of discordant xenografts”,Transplantation, 57(7):1003-1009 (1994).
Leventhal et al., “Removal of baboon and human antiporcine IgG and IgM natural antibodies by immunoadsorption. Results of in vitro and in vivo studies”,Transplantation, 59(2):294-300 (1995).
Geller et al., “Evidence that polyreactive antibodies are deposited in rejected discordant xenografts”,Transplantation, 55(1):168-172 (1993).
Koren et al., “Murine monoclonal anti-idiotypic antibodies directed against human anti-αGal antibodies prevent rejection of pig cells in culture: implications for pig-to-human organ xenotransplantation”,Transplant. Proc., 28(2):559 (1996).
Leventhal et al., “The synergistic effect of combined antibody and complement depletion on discordant cardiac xenograft survival in nonhuman primates”,Transplantation, 57(6):974-978 (1994).
Pruitt et al. “The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts”,Transplantation, 57(3):363-370 (1994).
Neethling et al., “Immunoadsorption of natural antibodies from human serum by affinity chromatography using specific carbohydrates protects pig cells from cytotoxic destruction”,Transplant. Proc., 26(3):1378 (1994).
Neethling et al., “Protection of pig kidney (PK15) cells from the cytotoxic effect of anti-pig antibodies by α-galactosyl oligosaccharides”,Transplantation, 57(6):959-963 (1994).
Li et al., “Inhibition of human anti-αGal IgQ by oligosaccharides derived from porcine stomach mucin”,Xenotransplantation, 2:279-288 (1995).
Cooper et al., “Specific intravenous carbohydrate therapy: a new approach to the inhibition of antibody-mediated rejection following ABO-incompatible allografting and discordant xenografting”,Transplant. Proc., 25(1):377-378 (1993).
Sandrin et al., “Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis”,Nat. Med., 1(12):1261-1267 (1995).
Sharma et al., “Reduction in the level of Gal(α1,3)Gal in transgenic mice and pigs by the expression of an α(1,2)fucosyltransferase”,Proc. Natl. Acad Sci. USA, 93(14):7190-7195 (1996).
Koike et al., “Introduction of α(1,2)-fucosyltransferase and its effect on αGal epitopes in transgenic pig”,Xenotransplantation, 3:81-86 (1996).
Blakely et al., “Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection”,Transplantation, 58(10):1059-1066 (1994).
Seebach et al., “Xenogeneic human anti-pig cytotoxicity mediated by activated natural killer cells”,Xenotransplantation, 3:188-197 (1996).
Chou et al., “Identication of α-galactose (α-fucose)-asialo-GM1glycolipid expressed by subsets of rat dorsal root ganglion neurons”,J. Biol. Chem., 264(6):3409-3415 (1989).
Fujiwara et al., “Structure and distribution of N-linked oligosaccharide chains on various domains of mouse tumour laminin”,Biochem. J., 252(2):453-461 (1988).
Dasgupta et al., “Branched monosialo gangliosides of the lacto-series isolated from bovine erythrocytes: characterization of a novel ganglioside, NeuGc-isooctaosylceramide”,Arch. Biochem. Biophys., 310(2):373-384 (1994).
Wong, CH, “Enzymatic and Chemo-Enzymatic Synthesis of Carbohydrates”,Pure Appl. Chem., 67(10):1609-1616 (1995).
Seed, B., “An LFA-3 cDNA encodes a phospholipid-linked membrane protein homobgous to its receptor CD2”,Nature, 329(6142):840-842 (1987).
Khodadoust et al., “PEC-A: An immortalized porcine aortic endothelial cell”,Xenotransplantation, 2:79-87 (1995).
Dabkowski et al., “Characterisation of a cDNA clone encoding the pig α1,3 galactosyltransferase: implications for xenotransplantation”,Transplant. Proc., 25(5):2921 (1993).
Dabkowski et al., “Isolation of a cDNA clone encoding the pig α 1,3 galactosyltransferase”,Transplant. Proc., 26(3):1335 (1994).
Gustafsson et al., “α 1,3galactosyltransferase: a target for in vivo genetic manipulation in xenotransplantati
Gustafsson Anki
Holgersson Jan
Liu Jining
Elrifi Ivor R.
Kozakiewicz Cynthia A.
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
O'Hara Eileen B
Recopharma AB
LandOfFree
Fusion proteins and methods of producing same does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fusion proteins and methods of producing same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fusion proteins and methods of producing same will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4103037