Fusion polypeptide comprising two ligand binding domains

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C435S325000, C530S350000, C536S023400

Reexamination Certificate

active

07011972

ABSTRACT:
Single chain, monomeric polypeptide gene switches are provided. The gene switches include ligand binding domains and at least one functional domain. Preferred functional domains are DNA binding domains and transcriptional regulating domains. Methods of regulating gene function using the switches are also provided.

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