Fusion of jAZF1 and jjAZ1 genes in endometrial stromal tumors

Details Fusion of jAZF1 and jjAZ1 genes in endometrial stromal tumors Fusion of jAZF1 and jjAZ1 genes in endometrial stromal tumors

2006-08-29

2006-08-29

Canella, Karen A. (Department: 1643)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C424S277100

Reexamination Certificate

active

07098311

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated jAZF1, jjAZ1 or jAZF1/jjAZ1 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing jAZF1, jjAZ1 or jAZF1/jjAZ1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a jAZF1, jjAZ1 or jAZF1/jjAZ1 gene has been introduced or disrupted. The invention still further provides isolated jAZF1, jjAZ1 or jAZF1/jjAZ1 proteins, fusion proteins, antigenic peptides and anti-jAZF1, jjAZ1 or jAZF1/jjAZ1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

REFERENCES:
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Database GenBank, Accession No. AK000711, Direct Submission, Sugano, S., et al. Feb. 15, 2000; the eDNA molecule comprises a polynucleotide sequence that is 100% identical to a polynucleotide sequence of SEQ ID No. 3.

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