Fused tricyclic heterocycles useful for treating...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S291000, C514S337000, C514S365000, C514S374000, C514S443000, C514S450000, C514S454000, C514S463000, C514S468000, C546S083000, C546S284100, C548S200000, C548S236000, C549S043000, C549S057000, C549S350000, C549S387000, C549S433000, C549S436000, C549S458000, C544S405000

Reexamination Certificate

active

07144885

ABSTRACT:
This invention relates to a novel fused tricyclic heterocycle of the formula (Ia, Ib) and its use for the treatment of hyper-proliferative disorders

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Patent Abstracts of Japan, vol. 009, No. 205 (C-299), Aug. 22, 1985 and JP 60 072880 A (Kaken Seiyaku KK), Apr. 24, 1985.
Hayakawa, et al., “4-Hydroxy-3-Methyl-6-Phenylbenzofuran-2-Carboxylic Acid Ethyl Ester Derivatives as Potent Anti-Tumor Agents,”Bioorg. Med. Chem. Lett., 14, 455-458 (2004).
Hayakawa, et al., “A Library Synthesis of 4-Hydroxy-3-Methyl-6-Phenylbenzofuran-2-Carboxylic Acid Ethyl Ester Derivatives as Anti-Tumor Agents,”Bioorg. Med. Chem. Lett., 14, 4383-4387 (2004).
Hayakawa, et al., “Thienopyridine and Benzofuran Derivatives as Potent Anti-Tumor Agents Possessing Different Structure-Activity Relationships,”Bioorg. Med. Chem. Lett., 14, 3411-3414 (2004).

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