Fused-thiazole derivatives active on the cholinergic system, and

Details Fused-thiazole derivatives active on the cholinergic system, and Fused-thiazole derivatives active on the cholinergic system, and

1993-05-28

1995-01-03

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514321, 514342, 514366, 514338, 546209, 546270, 546280, 544133, 544367, C07D27784, C07D41712, C07D40112, A61K 31425

Patent

active

053787064

ABSTRACT:
The invention relates to thiazole derivatives corresponding to the general formula: ##STR1## in which: - R.sub.1 and R.sub.2 each independently represent hydrogen; a C.sub.1 -C.sub.4 alkyl group; a phenyl group or a phenyl group monosubstituted or polysubstituted by a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy, nitro or hydroxyl group; or one of the groups R.sub.1 and R.sub.2 denotes hydrogen and the other represents a naphthyl group; a benzyl group; an .alpha.,.alpha.-dimethyl-benzyl group; a cyclohexyl group; a biphenyl group; a thienyl group or an adamantyl group; or alternatively R.sub.1 and R.sub.2, taken together, represent a group; ##STR2## in which the phenyl group is bonded to the 4-position of the thiazole and the group (CH.sub.2).sub.m to the 5-position, m represents an integer equal to 2 or 3 and R.sub.5 denotes hydrogen or a nitro group, R.sub.3 is H or an alkyl group and R.sub.4 is notably an alkyl substituted by an amino group, a pyrrolidino, or a pydridino group.

REFERENCES:
patent: 4064244 (1977-12-01), Sorg
patent: 4241072 (1980-12-01), Bolhofer
patent: 4517196 (1985-05-01), Schlecker et al.
Chem. Abstracts, vol. 75(21), Abst. No. 129,703-J dated Nov. 22, 1971.

Affiliated with

Also associated with

Rating

Fused-thiazole derivatives active on the cholinergic system, and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fused-thiazole derivatives active on the cholinergic system, and, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fused-thiazole derivatives active on the cholinergic system, and will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2211650