Fused ring thrombin receptor antagonists

Details Fused ring thrombin receptor antagonists Fused ring thrombin receptor antagonists

2011-08-23

2011-08-23

Skowronek, Karlheinz R (Department: 1613)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S217000

Reexamination Certificate

active

08003803

ABSTRACT:
Fused-ring, heterocyclic-substituted tricyclics of the formulaor a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein  represents an optional double bond, and wherein An, En, Mn, Gn, Jn, R3, n7, R8, R9, R10, R11, R32, R33, X, Y, B and Het are herein defined and the remaining substituents are as defined in the specification, are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. Combination therapy with other cardiovascular agents is also claimed.

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