Fused ring N-[1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-

Details Fused ring N-[1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine- Fused ring N-[1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-

1974-05-28

1976-05-25

Ford, John M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424249, 26029371, 26029369, 260250Q, 2602938, C07D25308

Patent

active

039592758

ABSTRACT:
Preparation of the subject compounds by reaction of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid with an N-hydroxy compound of the type HO--N Q wherein ##EQU1## represents an optionally substituted monocyclic- or fused polycylic-heterocyclic radical containing at least one carbonyl function adjacent the nitrogen atom, in the presence of a suitable dehydrating agent, and their useful biological properties, including analgesic and especially potent antidiarrheal activity are disclosed.

REFERENCES:
patent: 3847923 (1974-11-01), Kreider

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