Fused ring heterocycles and pharmaceutical compositions containi

Details Fused ring heterocycles and pharmaceutical compositions containi Fused ring heterocycles and pharmaceutical compositions containi

1990-08-14

1993-03-09

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548406, 548472, 548482, 548543, 546140, C07D20946, A61K 3140

Patent

active

051927918

ABSTRACT:
A novel class of pyrrolidin-2-one and piperidin-2-one compounds in which the nitrogen atom is bonded to an oxyphenyl radical having tertiary-alkyl and tri-methylsilyl substituents. The compounds possess anti-inflammatory, immunomodulatory, analgesic and anti-pyretic activity and they may be combined with excipients to provide formulations which are useful in treating arthritis and conditions associated with that disease.

REFERENCES:
patent: 4166125 (1979-08-01), Kigasawa et al.
patent: 4954514 (1990-09-01), Kita et al.

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