Fused quinazolinones and preparation thereof

Details Fused quinazolinones and preparation thereof Fused quinazolinones and preparation thereof

1978-01-31

1980-01-15

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544247, 544250, 544251, 544286, 544292, A61K 3141, C07D48704, C07D48714

Patent

active

041839323

ABSTRACT:
Tricyclic quinazolines of the formula, ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and A are as defined in the specification, such as 4,5-dihydro-5-arylimidazo[1,2-a]quinazolines, 4,5-dihydro-5-aryl-s-triazolo[4,3-a]quinazolines and 4,5-dihydro-5-aryltetrazolo[1,5-a]quinazolines having anti-inflammatory and analgesic activity are, for example, prepared by reducing the corresponding 4,5-unsaturated compounds, and then, if necessary, by alkylating the thus produced compounds.

REFERENCES:
patent: 4002755 (1977-01-01), Yamamoto et al.
patent: 4056384 (1977-11-01), Bowie et al.
patent: 4085212 (1978-04-01), Burrell et al.
patent: 4085213 (1978-04-01), Bindra
patent: 4087422 (1978-05-01), Bowie
Bogatskii, et al., "Chemical Abstracts," Vol. 88, 1978, col. 6829r.

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