Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-08-30
2005-08-30
Shameem, Golam M M (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S516000
Reexamination Certificate
active
06936632
ABSTRACT:
The present invention relates to fused pyrrole compounds of the formula 1.in which at least one of the radicals R1, R2, R3 is 4-sulphur-substituted phenyl.These compounds are in particular pyrrolizines, indolizines and heteroanalogues having selective inhibitory action on isoenzyme-2 of prostaglandin H synthase (COX-2). The invention also relates to pharmaceutical compositions which contain these compounds; and the use of these compounds for the treatment of disorders of the rheumatic type.
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Laufer Stefan
Striegel Hans-Guenter
Tollmann Karola
Tries Susanne
Merckle GmbH
Rothwell, Figg Ernst & Manbeck, PC
Shameem Golam M M
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