Fused pyrimidine compounds and their use as pharmaceuticals

Details Fused pyrimidine compounds and their use as pharmaceuticals Fused pyrimidine compounds and their use as pharmaceuticals

1994-06-06

1996-11-05

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544247, 544250, 544250, 544263, 544281, 548253, 548561, C07D48704, A61K 31505

Patent

active

055718132

ABSTRACT:
Pharmaceutical compounds which are azolo-fused pyrimidine compounds having the formula ##STR1## in which .dbd.A--B-- together with the pyrimidine ring forms a) a pyrazolo[1,5-a]pyrimidine of formula (A), ##STR2## b) a [1,2,4]triazolo[1,5-a]pyrimidine of formula (B), ##STR3## c) an imidazo[1,5-a]pyrimidine of formula (C), ##STR4## or d) an imidazo[1,2-a]pyrimidine of formula (D), ##STR5##

REFERENCES:
A. Burger, Prog. Drug Res. 1991-pp. 298-328.
Abstract of JP 72-78150 (Oct. 24, 1995).
Justus Liebigs, Annalen der Chemie, vol. 699, 1966, Verlag Chemie GmbH, R. Kuhn, Cover page and pp. 127-132; "Nucleophile substitutionen an 5-chlor-7-methyl-2-phenyl-imidazo[1.2-a]pyrimidinen;" T. Pyl et al.

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