Fused pyridines active on the cardiovascular system

Details Fused pyridines active on the cardiovascular system Fused pyridines active on the cardiovascular system

1989-07-25

1991-06-18

Rivers, Diana

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142345, 514248, 514258, 514300, 544117, 544127, 544236, 544279, 546113, 546123, A61K 31435, A61K 31495, A61K 3150, C07D47104

Patent

active

050250116

ABSTRACT:
Compounds of the formula ##STR1## (wherein Ar, R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, X and m have the meanings given in the description), their preparation and pharmaceutical compositions containing them.
The compounds of formula I are active on the cardiovascular system as antivasospastics, antiangina pectoris agents, antihypertensives and vasodilators.

REFERENCES:
patent: 4134980 (1979-01-01), Eberlein et al.
patent: 4145432 (1979-03-01), Sato
patent: 4223142 (1980-09-01), Denzel et al.
patent: 4438128 (1984-03-01), Wiedemann et al.
Kleinschroth et al., Chemical Abstracts, vol. 105, No. 72685 (1986) (Abstract for DE 3438350 or EP 180833).
Sostanze Farmaceutiche by Kleeman & Engel, pp. 1, 115, 169, 198, 264, 269, 285, 296, 298, 311, 337, 365, 960, 1012, 1079, 1130, 1142, 1181, 1213, 1299, 1313, 1346, 1444, 1504, 1606, 1607, 1635, 1718 (1988).
Chemical Abstracts, Sato et al, 88:170127f, p. 592, 1978.

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