Fused protein, gene therefor, recombinant vector,...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C424S192100, C530S350000

Reexamination Certificate

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07348422

ABSTRACT:
A DNA coding for a fusion protein comprising a polypeptide having the antigenicity ofMycoplasma gallisepticumand a polypeptide derived from Herpesvirus outer membrane protein, in which the polypeptide derived from the outer membrane protein has been ligated with the polypeptide having the antigenicity ofMycoplasma gallisepticumat the N terminus thereof, is prepared. The DNA is inserted into a region non-essential to growth of Avipox virus and the resulting recombinant Avipox virus is provided as a more potent recombinant virus as an anti-Mycoplasma vaccine.

REFERENCES:
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patent: 345021 (1989-12-01), None
patent: 404576 (1990-12-01), None
patent: WO 94/23019 (1994-10-01), None
Blacklaws et al. 1990. Virology. vol. 177: 727-736, 1990.
Calvert et al. 1993. J. of Virology. vol. 67(6): 3069-3076, 1993.
Nazerian et al. 1992. J. of Virology. vol. 66 No. 3: 1409-1413, 1992.
Yoshida et al. 1994. vol. 200: 484-493, 1994.
Yoshida et al. 1994. vol. 204: 414-419, 1990.
Yoshida et al.; Virology 200, pp. 484-493, 1994. See PCT Search Report.
Nazerian et al.; Journal of Virology, vol. 66, No. 3, pp. 1409-1413, Mar. 1992. See PCT Search Report.
DeLuca et al., Virology 122, pp. 411-423, 1982. See p. 4 of the specification.
Blacklaws et al., Virology 177, pp. 723-736, 1990. See p. 4 of the specification.

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