Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1995-06-06
1998-09-15
Kemmerer, Elizabeth C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530350, 530397, 435 697, C07K 1454, C07K 1400
Patent
active
058079963
ABSTRACT:
Mammalian proteins and muteins thereof, designated interleukin-4s (IL-4s), are provided which exhibit both B cell growth factor activity and T cell growth factor activity. Compounds of the invention include native human and murine IL-4s, muteins thereof, and nucleic acids which are effectively homologous to disclosed cDNAs, and/or which are capable of coding for mammalian IL-4s and their muteins.
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Nagata, et al.,
Arai Ken-ichi
Lee Frank
Mosmann Timothy
Rennick Donna
Yokota Takashi
Dulak Norman C.
Kemmerer Elizabeth C.
Schering Corporation
Thampoe Immac J.
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