Fused imidazole derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S413000, C514S414000, C514S445000, C546S121000, C549S062000, C549S070000

Reexamination Certificate

active

08030327

ABSTRACT:
The present invention relates to a compound represented by the Formula [I]:Wherein:the A ring is a 5-membered aromatic heterocyclic group containing at least one hetero atom selected from a nitrogen atom, and the like; A1and A2, are each a nitrogen atom, and the like; X2, X3, X4, and X5are all carbon atoms, or alternatively any one of X2, X3, X4, and X5is a nitrogen atom and the rest are all carbon atoms; R1is a hydrogen atom, or the like; R2, R3, R4, and R5, are each a hydrogen atom, or the like; R6and R6′, are each a hydrogen atom, and the like; R7is an aryl group and the like; and R8is an amino group or a hydroxy group,or a pharmaceutically acceptable salt or ester thereof.

REFERENCES:
patent: 7074801 (2006-07-01), Yoshida et al.
patent: 1277754 (2005-07-01), None
patent: WO 01/46196 (2001-06-01), None
patent: WO 02/34748 (2002-05-01), None
patent: WO 02/076983 (2002-10-01), None
patent: WO 03/092595 (2003-11-01), None
patent: WO 03/092595 (2003-11-01), None
patent: WO 2004/014899 (2004-02-01), None
Sausville, Edward et al., “Contributions of Human Tumor Xenografts to Anticancer Drug Development,” Cancer Research, vol. 66, pp. 3351-3354(2006).
Cecil Textbook of Medicine, edited by Lee Goldman and J. Claude Bennett, 21st Edition, vol. 1, Chapter 14, pp. 1060-1074 (2000).

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