Fused hybrid gene

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435 68, 435172, 536 27, C12N 120, C12N 1500, C12P 2100, C07H 2104

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044181493

ABSTRACT:
This invention is a process to produce specific proteins coded for by eukaryotic (or prokaryotic) DNA in bacteria. The invention, which uses recombinant DNA techniques, produces proteins in their natural, functional state unencumbered by extraneous peptides.

REFERENCES:
Dickson et al., Science vol. 187, pp. 27-35 (1975).
Metzler, Biochemistry, The Chemical Reactions of Living Cells, Academie Press Inc., pp. 907-910 (1977).
Backman et al., Cell, vol. 13, pp. 65-71, Jan. 1978.
Chang et al., Nature, vol. 275, pp. 617-624, Oct. 19, 1978.
Itakura et al., Science, vol. 198, pp. 1056-1063 (1977).
Backman et al., Proc. Natl. Acad. Sci. USA, vol. 73, pp. 4174-4178 (1976).

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