Fused heterobicyclo substituted phenyl metabotropic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S300000, C514S338000, C546S112000, C546S119000, C546S121000, C546S268700, C546S270100

Reexamination Certificate

active

07105533

ABSTRACT:
Phenyl compounds substituted with a fused-heterobicyclo moiety, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.

REFERENCES:
patent: 6124313 (2000-09-01), Grundler et al.
patent: 2001-35664 (2001-02-01), None
Lins, Claudio L, “Nitro- para- and meta-substituted 2-phenylindolizines as potential antimicrobial agents,” Journal of Pharmaceutical Sciences 71(5), pp. 556-561 (1982).
Nakatsuka et al., STN International (2005) HCAPLUS Database, Accession No. 2001:98819.
C. Lins et al., “Nitro- para- and meta-Substituted 2-Phenylindolizines as Potential Antimicrobial Agents”, Journal of Pharmaceutical Sciences, 71(5), pp. 556-561 (1982).

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