Fused compounds that inhibit vanilloid receptor subtype 1...

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

Reexamination Certificate

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C546S146000, C546S211000, C548S362500

Reexamination Certificate

active

08071762

ABSTRACT:
The present invention discloses novel compounds of general formula (I)or a pharmaceutically acceptable salt or prodrug thereof (in which X1-X5, R5-R8b, Z1-Z2and Ar1are defined herein), a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain in mammals, and pharmaceutical compositions including those compounds and a process for making those compounds.

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