Fused bicyclic pyrimidine derivatives

Details Fused bicyclic pyrimidine derivatives Fused bicyclic pyrimidine derivatives

2006-06-20

2006-06-20

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S221000, C514S228500, C514S234500, C514S252160, C514S262100, C540S460000, C540S502000

Reexamination Certificate

active

07064119

ABSTRACT:
A novel fused bicyclic pyrimidine derivative or a salt thereof that acts as a tachykinin receptor antagonist and, in particular, as an NK1 receptor antagonist is represented by the following general formula (1):wherein the rings A and B are each a benzene ring having 1 to 3 substituents (any adjacent two of which may be bound to one another to form a ring); the ring C is a nitrogen-containing ring; R is a hydrogen atom, a C1to C6alkyl group, a C1to C6alkylcarbonyl group, or a C1to C6alkylsulfonyl group; m is 1 or 2; and n is 2 or 3.

REFERENCES:
patent: 5770590 (1998-06-01), Natsugari et al.
patent: 9-263587 (1997-10-01), None
patent: 2002-348289 (2002-12-01), None

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