Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-06-08
1996-09-03
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540460, 540461, 540500, 540521, 540523, 544 47, 544235, 546183, C07D48704, C07D51304, C07D47104, A61K 3155
Patent
active
055524001
ABSTRACT:
Disclosed are compounds, compositions and methods for inhibiting interleukin-1.beta. protease activity. The compounds, bicyclic derivatives of aldehydes and .alpha.-substituted methyl ketones, have the formula (A) set out herein.
REFERENCES:
patent: 5366973 (1994-11-01), Flynn et al.
Miller, Annal NY Acad Sci b96, 133 (1993).
Chaturvedula Prasad V.
Dolle Roland E.
Ross Tina M.
Schmidt Stanley J.
Berch Mark L.
Davis William J.
DuPont Paul E.
Sterling Winthrop Inc.
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