Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Acyclic nitrogen double bonded to acyclic nitrogen – acyclic...
Patent
1994-10-21
1995-10-17
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Acyclic nitrogen double bonded to acyclic nitrogen, acyclic...
514381, 514382, 514510, 514535, 514562, 514563, 548253, 552 10, 560 10, 560 17, 560 45, 562427, 562428, 562431, 562455, A61K 3135, A61K 3141, A61K 31165
Patent
active
054591341
ABSTRACT:
A novel (fused) benz(thio)amide of the general formula: ##STR1## or a non-toxic salt thereof, wherein R.sup.4 represents:
(i) when B represents a closed ring, a group of the general formula: ##STR2## wherein U represents an oxygen atom or a sulfur atom; or (ii) when B represents a divalent group, a group of the general formula: ##STR3## wherein R.sup.5, R.sup.6, R.sup.7, R.sup.8, n, m, p and q are as defined in the specification, and exclusing certain compounds as defined in the specification, depending on whether A represents a single bond or a group. The compounds are useful for the prevention and/or treatment of diseases induced by leukotrienes, 5.alpha.-reductase, phospholipase and aldose reductase in mammals, especially human beings.
REFERENCES:
patent: 3549689 (1970-12-01), Frey et al.
patent: 3649637 (1972-03-01), Howes et al.
patent: 4205076 (1980-05-01), Durham et al.
patent: 4205079 (1980-05-01), Durham et al.
patent: 4935240 (1990-06-01), Nakai et al.
patent: 4994479 (1991-02-01), Mase et al.
Barker and Ellis, "Benzopyrones, Part III. Synthesis and Mass Spectra of Some Oxopyranobenzoxazolecarboxylic Esters," J. Chem. Soc.(C) (8), 1482-4 (1971).
Barker and Ellis, "Benzopyrones. Part IV. Pyrano[1,4]benzoxazinones and Some Dihydrobenzoxazines: Etc." J. Chem. Soc. (C) (11), 2079-82 (1971).
D. J. Drain, et al., "The Effects of Substituting Tetrazole for Carboxyl in Two Series of Anti-Inflammatory Phenoxyacetic Acids," J. Pharm. Pharmac., 1971, 23, 857-864.
Ellis et al., Chemical Abstracts, vol. 75, 20315h (1971).
Ellis et al., Chemical Abstracts, vol. 75, 5765m (1971).
Arai Yoshinobu
Miyamoto Tsumoru
Toda Masaaki
Ono Pharmaceutical Co. Ltd.
Raymond Richard L.
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