Fused antigen polypeptide

Details Fused antigen polypeptide Fused antigen polypeptide

1986-08-15

1990-07-03

Nucker, Christine M.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 697, 435 91, 435320, 935 41, 935 47, 935 56, 935 60, 935 73, 530350, 530808, 530806, 530825, 530826, C12N 120, C12N 1500, C07K 1300

Patent

active

049390945

ABSTRACT:
The present invention provides a hybrid antigen polypeptide having both antigenicity of the ATLA encoded by gag gene and that of the ATLA encoded by env gene. The hybrid antigen can be produced in a large amount and it is applicable to serum diagnosis of patients infected with antigen polypeptides such as ATLV.

REFERENCES:
patent: 4588681 (1986-05-01), Sawada et al.
patent: 4629783 (1986-12-01), Cosand
patent: 4722840 (1988-02-01), Valenzuela et al.
patent: 4724258 (1988-02-01), Yoshida et al.
patent: 4751180 (1988-06-01), Cousens et al.
Hatanaka et al., "The pX Region of HTLV-I", Chem. Abs. 105 (1986) 53379x.
Davis et al., "Immune Response to Human Influenza Virus Hemagglutin Expressed in Escherichia coli", Gene 21 (1983) 273-284.
Seiki et al., "Human Adult T-Cell Leukemia virus: Complete Nucleotide Sequence of the Provirus Genome Integrated in Leukemia Cell DNA", Pro. Natl. Acad. Sci., U.S.A., 80 (1983) 3618-3622.
Hattori et al., "Identification of gag and env Gene Products of Human T-Cell Leukemia Virus (HTLV)", Virol. 136 (1984) 338-347.
Gene, vol. 21, Nos. 1 and 2 (1983) 273:84.
P.N.A.S., vol. 80, No. 12 (1983) 3618:22.
Virology, vol. 136, No. 2 (1984) 338:47.

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