Furoxanthone derivatives useful as diuretics

Details Furoxanthone derivatives useful as diuretics Furoxanthone derivatives useful as diuretics

1985-09-12

1987-04-28

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549392, C07D31186

Patent

active

046616071

ABSTRACT:
Xanthone derivatives of the formula (I): ##STR1## (wherein W, X, Y and Z which may be the same or different represent a hydrogen atom, a halogen atom or a lower alkyl group having 1 to 4 carbon atoms; A is hydrogen atom or together with Z forms a --CH.sub.2 -- group which binds to a phenyl carbon adjacent the phenyl carbon to which the oxygen of the group ##STR2## is attached to form a cyclic methylene chain; B is a hydroxymethyl group, a lower alkoxycarbonyl group having 1 to 4 carbon atoms, or a carboxyl group, provided that W is neither a hydrogen atom nor a 7-position methyl group when X, Y and Z are each a hydrogen atom, and A is a hydrogen atom and B is a carboxyl group or a lower alkoxycarbonyl group), as well as non-toxic salts thereof when B is a carboxyl group, and a process for preparing the same are disclosed.
The compounds of formula (I) in accordance with the present invention are useful as diuretics having uricosuric activity and can be used in the treatment of edema or hypertension.

REFERENCES:
Puranik et al., C.A., 72, 55161v (1970).
Scheinmann, C.A., 57, 11979e (1962).

Affiliated with

Also associated with

Rating

Furoxanthone derivatives useful as diuretics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Furoxanthone derivatives useful as diuretics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Furoxanthone derivatives useful as diuretics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-478186