Furosemide salts and pharmaceutical preparations thereof

Details Furosemide salts and pharmaceutical preparations thereof Furosemide salts and pharmaceutical preparations thereof

1985-07-02

1987-05-05

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549494, A61K 3134, C07D30754

Patent

active

046633480

ABSTRACT:
Quaternary ammonium salts of furosemide are stable and highly water-soluble, affording thereby solid oral dosage forms which are more bioavailable, oral liquid dosage forms hitherto unavailable, and injectable dosage forms of furosemide with higher concentration, hence lower volume, which do not add to the sodium ion burden of patients to whom it may be administered.

REFERENCES:
patent: 3058882 (1962-10-01), Sturm et al.
patent: 3565920 (1971-02-01), Werner
patent: 4131678 (1978-12-01), Amachler et al.
patent: 4324779 (1982-04-01), Dahihausen et al.
patent: 4564625 (1986-01-01), Muschaweck et al.

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