Furazanobenzimidazoles

Details Furazanobenzimidazoles Furazanobenzimidazoles

2004-05-19

2011-11-01

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S364000

Reissue Patent

active

RE042890

ABSTRACT:
The invention relates to compounds of formula (I) wherein R represents aryl or heteroaryl, X is oxygen, a carbonyl group, an oxime derivative of a carbonyl group or an α,β-unsaturated carbonyl group, and the substituents R1to R6have the meanings given in the specification, for use as medicaments, to novel compounds of formula (I), to methods of synthesis of such compounds, to pharmaceutical compositions containing compounds of formula (I), to the use of a compounds of formula (I) for the preparation of a pharmaceutical composition for the treatment of neoplastic and autoimmune diseases, and to methods of treatment of neoplastic and autoimmune diseases using such compounds of formula (I) or of pharmaceutical compositions containing same

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Database Chemcats Online, Chemical Abstracts Service, Columbus, Ohio, US, XP002257451, Apr. 29, 2003.
Sergievskii A V et al: “4-Aminofurazan-3-Carvoxylic Acid Iminoester in Reactions with N,O-Nucelphiles” Russian Journal of Organic Chemistry, Consultants Bureau, US, vol. 38, No. 6, 2002, pp. 872-874.
Sergievskii A V et al: “Reactions of Methyl 4-Aminofurazan-3-Carboximidate With Nitrogen-Containing Nucleophiles”, Russian Journal of Organic Chemistry, Consultants Bureau, US, vol. 37, No. 5, 2001, pp. 717-720.
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