Furanone derivatives for the treatment of inflammation

Details Furanone derivatives for the treatment of inflammation Furanone derivatives for the treatment of inflammation

1992-09-25

1994-12-27

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3134

Patent

active

053766822

ABSTRACT:
The present invention relates to a method for reducing or treating inflammation in a mammal which comprises administering to the mammal an effective amount of at least one furanone derivative of the formula (I): ##STR1## wherein X is hydrogen, hydroxy, a lower alkyl group or a lower alkylene group; Y is hydrogen, hydroxy or a lower alkyl group; Z is hydrogen, a lower alkyl group or a lower hydroxyalkyl group; and the broken line represents the presence or absence of a second bond; or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 5045564 (1991-09-01), Lee
Tetrahedron Letters, vol. 28 (20), p. 2299 (1987).

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