Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-11-22
1995-09-26
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540503, 540560, 514220, 548532, 548533, 548536, 548537, 548539, 548540, A61K 3155, C07D491048, C07D491147
Patent
active
054534240
ABSTRACT:
This invention is concerned with novel compounds represented by structural formulae I and II. ##STR1## which are useful in the treatment of cardiac arrhythmia.
REFERENCES:
patent: 4775671 (1988-10-01), Hunkeler et al.
patent: 4992437 (1991-02-01), Naka et al.
Sanguinetti et al., Two Components Of Cardia Delayed Rectifier K+ Agents, J. Gen. Physiol., Jul., 1990, pp. 195-215.
Hondeghem, Development Of Class III Antiarrhythmic Agents, J. Cardiovasc. Pharmacol, 1992, vol. 20, (Supple. 2), pp. S17-S22.
Baldwin John J.
Ponticello Gerald S.
Remy David C.
Ayler Sylvia A.
Bernhardt Emily
Bigley Francis P.
Daniel Mark R.
Merck & Co. , Inc.
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