Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-24
1996-10-29
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 63, 514 80, 514140, 514147, 5142312, 5142395, 514317, 514383, 514388, 514399, 514433, 514471, A01N 4316, A01N 5700, A61K 3135, A61K 31675
Patent
active
055696716
ABSTRACT:
Novel compounds of formula I ##STR1## wherein R.sup.1 is independently hydrogen, hydroxy, alkyl with 1 to 6 carbon atoms, acyloxy groups with 1 to 6 carbon atoms, alkyloxy with 1 to 6 carbon atoms or from 1 to 5 sugar moieties; and R.sup.2 is independently hydrogen, or alkyl with 1 to 6 carbon atoms.
The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Ascochyta sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired formula I.
Disclosed is also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in valuable crops, animals, including birds and mammals, and in the preservation of wood, paints and edible products.
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Hooper et al. J. Chem. Soc., vol. 11, pp. 3580-3590 (1971).
Kurobane et al, Tetrahedron Letters, vol. 47, pp. 4633-4666 (1978).
Franck et al., Chemiche Berichte, vol. 99, No. 12, pp. 3842-3862 (1966).
Nielsen Ruby I.
Rasmussen Frank W.
Agris, Esq. Cheryl H.
Novo Nordisk A S
Robinson Allen J.
Zelson Esq. Steve T.
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