Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Patent
1992-10-06
1994-04-26
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
548110, A01N 5500, A61K 31695, C07D 708
Patent
active
053067126
ABSTRACT:
Compounds of formula (I): ##STR1## wherein: A is 1,2,4-triazol-1-yl or imidazol-1-yl; n is 0, 1, 2 or 3; X is halogen, phenyl, alkyl, haloalkyl, alkoxy, or haloalkoxy, or (X).sub.n is alkylenedioxy; R.sup.1 is alkyl or phenyl; and R.sup.2 and R.sup.3 are each alkyl; and salts thereof have valuable anti-fungal activity. Certain intermediates in the preparation of these compounds are also disclosed.
REFERENCES:
patent: 5134152 (1992-07-01), Takeshiba et al.
Chemical Abstracts, vol. 116, 1992, Columbus, Ohio, US; Abstract No. 59045k, Konosu et al.
Hudrlik et al, Tetrahedron Letters, "Rearrangements of .beta.,.gamma.-Epoxysilanes to .beta.-Silyl Aldehydes and Ketones", No. 1, 1976, pp. 29-32, Pergamon Press.
Kato Shigehiro
Kondo Yasuhiko
Ohta Hiroshi
Takeshiba Hideo
Tobitsuka Junzo
Morris Patricia L.
Sanyo Company, Limited
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