Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-01-02
2000-05-23
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 63, 514248, 514249, 514259, 514262, 514267, 544229, 544236, 544237, 544249, 544255, 544256, 544257, 544258, 544265, 544278, 544279, 544280, 544284, 544285, 544287, 544290, A61K 31505, C07D49304, C07D49504
Patent
active
060666382
DESCRIPTION:
BRIEF SUMMARY
BACKGROUND OF THE INVENTION
This invention relates to certain pyrimidinones, their N-oxides, agriculturally suitable salts and compositions, and methods of their use as fungicides.
The control of plant diseases caused by fungal plant pathogens is extremely important in achieving high crop efficiency. Plant disease damage to ornamental, vegetable, field, cereal, and fruit crops can cause significant reduction in productivity and thereby result in increased costs to the consumer. Many products are commercially available for these purposes, but the need continues for new compounds which are more effective, less costly, less toxic, environmentally safer or have different modes of action.
DT 2,210,503, DT 2,411,274, DT 2,411,273, and DD-A-240,892 disclose certain thienopyrimidine compounds. These publications, however, do not disclose the compounds of the present invention nor agricultural fungicide utility. U.S. Pat. No. 3,755,582 and U.S. Pat. No. 3,867,384 disclose certain 4(3H)-quinazolinone fungicides. These publications, however, do not disclose the compounds of the present invention.
SUMMARY OF THE INVENTION
This invention is directed to compounds of Formula I including all geometric and stereoisomers, N-oxides, and agriculturally suitable salts thereof, agricultural compositions containing them and their use as fungicides: ##STR2## wherein W is O, S(O).sub.n or NR.sup.5 ; thiazole, oxazole, imidazole, pyrazine, pyridazine or pyrimidine ring; -C.sub.10 alkenyl; C.sub.3 -C.sub.10 alkynyl; C.sub.1 -C.sub.10 haloalkyl; C.sub.3 -C.sub.10 haloalkenyl; C.sub.3 -C.sub.10 haloalkynyl; C.sub.2 -C.sub.10 alkoxyalkyl; C.sub.2 -C.sub.10 alkylthioalkyl; C.sub.2 -C.sub.10 alkylsulfonylalkyl; C.sub.4 -C.sub.10 cycloalkylalkyl; C.sub.4 -C.sub.10 alkenyloxyalkyl; C.sub.4 -C.sub.10 alkynyloxyalkyl; C.sub.4 -C.sub.10 alkenylthioalkyl; C.sub.4 -C.sub.10 alkynylthioalkyl; C.sub.2 -C.sub.10 haloalkoxyalkyl; C.sub.4 -C.sub.10 alkoxyalkenyl; C.sub.4 -C.sub.10 alkylthioalkenyl; C.sub.4 -C.sub.10 trialkylsilylalkyl; C.sub.1 -C.sub.10 alkoxy; NR.sup.6 R.sup.7 ; R.sup.11 ; phenyl, pyridinyl, furanyl, thienyl, naphthalenyl, benzofuranyl, benzo[b]thiophenyl or quinolinyl each optionally substituted with R.sup.8, R.sup.9 and R.sup.10 ; or C.sub.1 -C.sub.10 alkyl substituted with NR.sup.6 R.sup.7, nitro, cyano, CO.sub.2 R.sup.6, or phenyl optionally substituted with R.sup.8, R.sup.9 and R.sup.10 ; -C.sub.10 alkenyl; C.sub.3 -C.sub.10 alkynyl; C.sub.1 -C.sub.10 haloalkyl; C.sub.3 -C.sub.10 haloalkenyl; C.sub.3 -C.sub.10 haloalkynyl; C.sub.2 -C.sub.10 alkoxyalkyl; C.sub.2 -C.sub.10 alkylthioalkyl; C.sub.2 -C.sub.10 alkylsulfonylalkyl; C.sub.4 -C.sub.10 cycloalkylalkyl; C.sub.4 -C.sub.10 alkenyloxyalkyl; C.sub.4 -C.sub.10 alkynyloxyalkyl; C.sub.4 -C.sub.10 alkenylthioalkyl; C.sub.4 -C.sub.10 alkynylthioalkyl; C.sub.2 -C.sub.10 haloalkoxyalkyl; C.sub.4 -C.sub.10 alkoxyalkenyl; C.sub.4 -C.sub.10 alkylthioalkenyl; C.sub.4 -C.sub.10 trialkylsilylalkyl; R.sup.11 ; phenyl optionally substituted with R.sup.8, R.sup.9 and R.sup.10 ; or C.sub.1 -C.sub.10 alkyl substituted with NR.sup.6 R.sup.7, cyano, nitro, CO.sub.2 R.sup.6, or phenyl optionally substituted with R.sup.8, R.sup.9 and R.sup.10 ; or --OR.sup.7 ; --N.dbd.CR.sup.6 R.sup.6 ; --NR.sup.6 R.sup.7 ; and pyridinyl, furanyl, thienyl and naphthalenyl each optionally substituted with R.sup.8, R.sup.9 and R.sup.10 ; or --N.dbd.CR.sup.6 R.sup.6 and --NR.sup.6 R.sup.7 ; cycloalkyl; C.sub.2 -C.sub.8 alkenyl; C.sub.2 -C.sub.8 alkynyl; C.sub.1 -C.sub.8 haloalkyl; C.sub.3 -C.sub.8 haloalkenyl; C.sub.3 -C.sub.8 haloalkynyl; C.sub.1 -C.sub.8 alkoxy; C.sub.1 -C.sub.8 haloalkoxy; C.sub.3 -C.sub.8 alkenyloxy; C.sub.3 -C.sub.8 alkynyloxy; C.sub.1 -C.sub.8 alkylthio; C.sub.1 -C.sub.8 alkylsulfonyl; C.sub.2 -C.sub.8 alkoxyalkyl; C.sub.3 -C.sub.8 trialkylsilyl; nitro; NR.sup.6 R.sup.7 ; C.sub.5 -C.sub.8 trialkylsilylalkynyl; or phenyl optionally substituted with at least one R.sup.13 ; haloalkyl, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 haloalkoxy; optionally substituted with at least one R.sup.13 ; op
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Bereznak James Francis
Chang Zen-Yu
Sternberg Charlene Gross
E. I. Du Pont de Nemours and Company
Raymond Richard L.
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