Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1985-09-20
1988-02-16
Brown, J. R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514967, 514968, 514 21, 424 54, A61K 3702, A61K 716
Patent
active
047255765
ABSTRACT:
Polypeptides containing a substantial proportion of L-histidine are effective fungicidal agents. They are particularly effective against C. albicans and have a high degree of safety and nontoxicity because of their structural similarity to naturally occuring histidine-rich polypeptides which are unique to the salivas of humans and old world monkeys.
REFERENCES:
patent: 3497591 (1970-02-01), Yankell et al.
patent: 4154813 (1979-05-01), Kleinberg
Baum et al., Arch Biochem. Biophys. 177, 427-436 (1976).
Baum et al., J. Dent. Res. pp. 1115-1118, Sep. 1977.
Peters et al., Biochem. Genetics, vol. 15, Nos. 9/10, 1977, pp. 925-946.
Katchalski et al., in The Proteins, 2nd Ed., vol. II, 1964, pp. 405-406, 577-578, 587, 597.
Renner et al., Oral Surg., vol. 47, No. 4, 1979, pp. 323-328.
Budtz-Jorgensen, JADA 9, 1978, pp. 474-479.
Tarbet, J. Prosthet. Dent., vol. 48, No. 6, 1982, pp. 647-652.
Budtz-Jorgensen, Scand. J. Dent. Res., 82, 1974, pp. 151-190.
Rubin et al., Proc. Soc. Exptl. Biol. Med. 82, 1953, pp. 231-234.
Yphantis et al., J. Bacteriol. 1967, pp. 1509-1515, vol. 94, No. 5.
Gibson et al., Anal. Biochem, 96, 1979, pp. 352-354.
Peters et al., Biochem. Genetics, vol. 15, Nos. 9/10, 1977, pp. 947-962.
Davenport, Brit. Dent. J., 129, 1970, pp. 151-156.
Balekjian et al., Biochem. Biophys. Res. Comm., vol. 50, No. 3, 1973, pp. 676-682.
Budtz-Jorgensen, Acta Odontolog. Scand. 28, 1970, pp. 71-90.
Hay, cited in Chem. Abstracts, vol. 84:2691j., 1976.
MacKay Bruce J.
Pollock Jerry J.
Behr Omri M.
Brown J. R.
Research Foundation of State University of New York
Stone Jacqueline M.
LandOfFree
Fungicidal polypeptide compositions containing L-histidine and m does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fungicidal polypeptide compositions containing L-histidine and m, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fungicidal polypeptide compositions containing L-histidine and m will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2221193