Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1989-10-03
1992-06-23
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
71 76, 71 88, 71 90, 71 92, 71 94, 71 95, 71 98, 71108, 514269, 514532, 544334, 544335, 560 10, 560 15, 560 17, 560 56, 560 57, 560 59, 560 60, 560 61, 560 62, A01N 3710, C07C 69612
Patent
active
051243539
ABSTRACT:
Compounds of formula (I): ##STR1## and stereoisomers thereof, wherein V is an oxygen or a sulphur atom; X and Y, which may be the same or different, are hydrogen or halogen atoms, or optionally substituted alkyl, optionally substituted alkenyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkynyl, haloalkyl, alkoxy, haloalkoxy, optionally substituted aryloxy, optionally substituted arylalkoxy, optionally substituted acyloxy, optionally substituted amino, acylamino, nitro, nitrile, --CO.sub.2 R.sup.3, --CONR.sup.4 R.sup.5, or --COR.sup.6 groups; or the groups X and Y, when they are in adjacent positions on the phenyl ring, may join to form a fused ring, either aromatic or aliphatic, optionally containing one or more heteroatoms; and Z is optionally substituted methylene, optionally substituted amino, oxygen or sulphur and when Z is a substituted methylene group, the substituent may join the 2-position of the phenyl ring to form a non-aromatic fused ring; R.sup.1 and R.sup.2 are alkyl groups containing from one to four carbon atoms, optionally substituted with one or more halogen atoms; and R.sup.3, R.sup.4, R.sup.5, and R.sup.6, which may be the same or different, are hydrogen atoms or optionally substituted alkyl, cycloalkyl, alkenyl, alkynyl, optionally substituted aryl, optionally substituted aralkyl, or cycloalkylalkyl groups: and metal complexes thereof.
REFERENCES:
patent: 3922345 (1975-11-01), Lipinski
patent: 3941889 (1976-03-01), Lipinski
patent: 4104049 (1978-08-01), Maurer et al.
patent: 4267355 (1981-05-01), Scott et al.
patent: 4492683 (1985-01-01), Nagpal
Tanaka, et al., "Chemical Abstracts", vol. 90, 1979, col. 90:22469y.
Chemical Abstracts 55 17492c (Rec. Trav. Chim. 79 937-49 (1960).
Chemical Abstracts 55 27350c (J. Org. Chem. 26 2770-8 (1961).
Chemical Abstracts 90 22469v (Chem. Pharm. Bull. 26(5) 1558-69 (1978).
Chemical Abstracts 90 71791c (Chem. Ber. 111 (12) 3879-91).
Chemical Abstracts 95 186931u (J. Chem. Res. 1981(7). 18C-1).
Clough John M.
Godfrey Christopher R. A.
Imperial Chemical Industries plc
Ivy C. Warren
Turnipseed James H.
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